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This type of dual-action strategy is particularly appealing for individuals interested in both immediate performance and long-term brain resilience
Compounding is restricted or requires additional oversight
As well as treating type 2 diabetes, trials have shown that SGLT-2 inhibitors can also lower the risk of heart failure and kidney disease, but their effect on recurrent kidney stones and gout flare-ups is still uncertain
The 2025 Am J Gastroenterology: Better Outcomes, Not Worse A separate multicenter analysis, published in American Journal of Gastroenterology (May 2025), extended the question beyond risk to outcomes
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